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Sally field movies5/21/2023 Her other memorable film credits include "Where the Heart Is" (2000) with Natalie Portman and Ashley Judd, and "Homeward Bound: The Incredible Journey" (1993).Īmerican actress, producer, and director born on 6 November 1946 in Pasadena, California. The first time I didn't feel it, but this time I feel it-and I can't deny the fact that you like me, right now, you like me!" Throughout her long career, Field has also earned three Emmy Awards, two Golden Globes, the SAG Best Actress award, and the Best Female Performance Prize at Cannes for "Norma Rae." Her turn as the First Lady in "Lincoln" earned her nominations at the Oscars, Golden Globes, BAFTAs and SAG Awards. Field has won two Oscars for Best Actress for "Norma Rae" and "Places in the Heart." Her breathy, often quoted acceptance speech is remembered for her jubilant outburst "I haven't had an orthodox career, and I've wanted more than anything to have your respect. She was born in Pasadena, California, on November 6, 1964.Read more She's had lead roles on film and television in every decade since the 1960s: "Gidget" (1965-66), "The Flying Nun" (1967-70), "Sybil" (1976), "Smokey and the Bandit" (1977), "Norma Rae" (1979), "Absence of Malice" (1981), "Places in the Heart" (1984), "Steel Magnolias" (1989), "Not Without My Daughter" (1991), "Mrs. Sally does not stop and we hope she never does.Sally Field is an American actress, singer, producer, director, screenwriter and one of America's original sweethearts. Every stage of an actor’s life brings different opportunities, and you just need to keep working. Sally is a massive star with a working actor’s ethos – just keep doing the work, being as good as you can. That’s part of why she has sustained her massive fandom and incredibly rich and layered career. “She has an enduring career because she is authentic in her performance and always projects likability and humanity – she just connects. She never stopped being extraordinary, including as recently as Winning Time in which she was simply sublime as Jessie Buss,” SAG-AFTRA president Fran Drescher said in a statement. I joyfully watched her early career when she portrayed Gidget and the Flying Nun and then, in ever more challenging roles, as Sybil and Norma Rae. “Sally is an amazing actor with an enormous range and an uncanny ability to embody any character. In theater, she made her Broadway debut in Edward Albee’s The Goat and also starred in The Glass Menagerie and All My Sons. The actress also has numerous TV and theater credits to her name: on the TV side, she starred in The Flying Nun, Sybil, ER, Brothers & Sisters, Winning Time, Maniac and Dispatches From Elsewhere. She most recently starred in Michael Showalter’s Spoiler Alert and will next star in 80 for Brady alongside Jane Fonda, Lily Tomlin and Rita Moreno. Doubtfire, Hooper, Stay Hungry and Hello, My Name Is Doris, among many others. Her career credits include Places in the Heart, Norma Rae, Lincoln, Smokey and the Bandit, Absence of Malice, Kiss Me Goodbye, Steel Magnolias, Forrest Gump, An Eye for an Eye, Mrs. Nicole Kidman's AFI Life Achievement Award Event Postponed Due to Writers Strike
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Qnap qvr client5/21/2023 With Linux and ZFS, QuTS hero supports advanced data reduction technologies for further driving down costs and increasing reliablility of SSD (all-flash) storage. Compruebe el NAS de QNAP con soporte para la aplicación de virtualización Verificado como objeto Veeam Ready QuObjects está verificado como Veeam® Ready, lo que garantiza tanto la compatibilidad como la fiabilidad para lograr una recuperación y una copia de seguridad eficientes con Veeam Backup & Replication. QTS/QuTS hero Surveillance Perpetual Buy USD 29. You can easily find events with Smart Search and check the results on the Timeline. QuTS hero is the operating system for high-end and enterprise QNAP NAS models. QVR Smart Client allows you to directly view surveillance footage by connecting the NAS with an HDMI output to an HDMI display. WIth Linux and ext4, QTS enables reliable storage for everyone with versatile value-added features and apps, such as snapshots, Plex media servers, and easy access of your personal cloud. Displays camera locations and event icons on E-maps to allow for comprehensive monitoring.QTS is the operating system for entry- and mid-level QNAP NAS. Provides the option to click snapshots in event logs to play back previous events. Note: For these services to operate correctly, their ports should remain open. The most common release is 5.0, with over 98 of all installations currently using. These ports are assigned to a specific service and users must manually open the required ports by adding the port number. QNAP QVR Client is a software program developed by QNAP Systems. Supports sending instant push notifications. QNAPuses designated ports for communication. 5.3 Remote Monitoring from the QNAP QVR Client for Windows. Provides various advanced monitoring options: Sequential mode, PTZ control, auto cruising and preset point control. Little-known anti-malware programs display warnings, which are often identified as false positive. View the QNAP VS-8124 PRO+ manual for free or ask your question to other QNAP VS-8124 PRO+. Supports switching instantly between the Live and Playback modes and clicking the timeline to play back recordings from a specific moment. Fixed a command injection vulnerability (CVE-2021-28800). QVR Pro Client 2.3.0: Export with watermarking, LPR event search and privilege enhancement. QNAP QVR Client is a client application that allows users to easily configure recording settings of the IP cameras, while also providing local or remote access. Supports viewing multiple IP cameras connected to QVR Pro. Container Station (or later) must be installed before QVR Pro can be used.x86-based (64-bit) QNAP NAS with at least 4GB RAM (8GB RAM is recommended for the. After updating QTS to 4.5.3 (or later), Surveillance Station users can download and install the latest version of QVR Client from the QNAP website: QNAP Utilities Security Updates - Fixed a DOM-based cross-site scripting vulnerability (CVE-2021-28806). QVR Pro 2.4.0: Support for License Plate Recognition and more Video Content Analysis events. QVR Pro 1.1.0 is required for querying event logs. The latest version of QTS 4.3.4 is required for enabling push notifications and activating licenses. QuTS hero is the operating system for high-end and enterprise QNAP NAS models. QVR Pro / Elite installed and initialized on the QNAP NAS running QTS 4.3.0 The QVR Pro Client client software can be installed on Windows and Mac devices or in QNAPs HD Station on NAS, allowing you to monitor from different. QVR Pro Client provides an intuitive interface for your QVR Pro / Elite server, helping you manage IP cameras, monitor live views, and play back previous recordings using your mobile devices.
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Peg solitaire formula5/21/2023 Klondike is also known as Canfield, named for Richard Albert Canfield, who at one time was "the best known and wealthiest individual gambler in the world." He ran several gambling houses, including, most famously, the Old Saratoga Club in Saratoga Springs, New York. ( Racing demon, by the way, is when several people play demon at once and competitively.) Klondike, which has been around since at least 1902, might be named for the Klondike gold rush of the late 1890s, perhaps with the idea of luck or winnings. Mopp, a character in the 1940s BBC radio show I.T.M.A, or It's That Man Again.ĭemon might be named for the number of cards in the reserve, an unlucky 13. Mop, which was invented by British stamp collector Charles Jewell and named for Mrs. Muggins also means "fool" or "simpleton." It's what players shout to the loser in a children's game of the same name. There's Muggins, which might refer to a variety of easily fooled characters (all named Muggins for some reason) in 18th and 19th-century comic writing. Still other varieties seem to be named for stock characters. But why "grand" names are favored - like the Empress of India, the Shah, the Grand Duchess, and the Queen of Italy - isn’t so evident. Some are obviously named for the shape of the set-up, such as the clock, the flower-garden, the herring-bone, and the spider. The more people played the games, the more quickly they became bored and needed variety - although it's unclear where some of the names come from. This might help to explain why both Patience and Solitaire developed into so many forms, even before the 20th century. At the same time, the rich became even richer, and leisure time increased. Unmarried adult children left to work in factories and other city industries, and, one can imagine, were left with more alone time than they were used to. The farm became less central and families less tight knit. into those that were industrial and urban. The Industrial Revolution, which began in Britain in the late 18th century, transformed rural societies in Europe and the U.S. Even back in 1874, the first book about the pastime refers to "games of solitaire or patience," with no distinction between the two.Īs for their simultaneous rise in popularity in different parts of the world, urbanization might have had something to do with it. While there might have been some difference between Solitaire and Patience at first, they now seem interchangeable. The first mention in English is from 1822 in a letter from a Countess Granville ("We were occupied all yesterday evening with conjuring tricks and patiences of every kind"). It's borrowed French: "I should be obliged to fetch the cards for you to play 'Grande Patience'" - giving some credence to the theory that the game originated in France. The OED has the earliest mention in 1801. The game of Patience originated in the U.K. around the same time as Solitaire, or slightly afterward. Moreover, in Scandinavian countries, the game is apparently known as cabale, which is related to cabal, a "mystical interpretation of the Old Testament." Cabal gives us Kabbalah, that mystical (and trendy) form of Judaism. Solitaire the card game more likely came about toward the end of the 18th century, perhaps "in the Baltic region of Europe and possibly as a form of fortune-telling." The theory is that the popularity of the game rose with the popularity of cartomancy, or divination by cards, as well as tarot card reading. However, this probably refers to peg solitaire, a board game played with marbles and pegs. The earliest printed reference of the world solitaire the game appeared in 1746, according to the Oxford English Dictionary ( OED). The exact origin of Solitaire isn't all that clear. For example, in Klondike, the objective is to uncover four aces and build sequential foundations from those cards. You're probably already familiar with the basic premise: You set up cards face down in a certain shape and flip them to build foundations in sequential order.
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Does ram improve my startup time5/21/2023 Go to a Previous Restore PointĪs you use Windows 10, it automatically creates restore points that are essentially snapshots of your system at specific moments in time, including installed software, drivers and updates. Now that you’ve selected all the programs that you want to disable at startup, the next time you restart your computer, the system will be a lot less concerned with unnecessary programs. You’ll usually find very solid information about the program or service. If you’re really nervous about one of the listed applications, you can go to a site run by Reason Software called Should I Block It? and search for the file name. Bing will then launch with links to sites with information about the program or service. You can also right-click the item and select “Open file location.” That opens File Explorer and takes it to the folder where the file is located, which may give you another clue about the program’s purpose.įinally, and most helpfully, you can select “Search online” after you right-click. Right-click an item and select “Properties” for more information about it, including its location on your hard disk, whether it has a digital signature, and other information such as the version number, the file size and the last time it was modified. The Task Manager helps you get information about unfamiliar programs. (Anyone who immediately knows what “bzbui.exe” is, please raise your hand. Many of the programs and services that run on startup may be familiar to you, like OneDrive or Evernote Clipper. You can use the Task Manager to help get information about programs that launch at startup and disable any you don't need. (Click image to enlarge it.) Also, if you later decide you want it to launch at startup, you can just return to this area of the Task Manager, right-click the application and select “Enable.” IDG To stop a program or service from launching at startup, right-click it and select “Disable.” This doesn't disable the program entirely it only prevents it from launching at startup - you can always run the application after launch. Included on the list is each program's name as well as its publisher, whether it's enabled to run on startup, and its “Startup impact,” which is how much it slows down Windows 10 when the system starts up. You'll see a list of the programs and services that launch when you start Windows. There's plenty you can do with it, but we're going to focus only on killing unnecessary programs that run at startup.Ĭlick the Startup tab. The Task Manager will then appear in all of its full-tabbed glory. If the Task Manager launches as a compact app with no tabs, click “More details” at the bottom of your screen. Start by launching the Task Manager: Press Ctrl-Shift-Esc, right-click the lower-right corner of your screen and select Task Manager, or type task manager into the Windows 10 search box and press Enter. Stop them from running, and your PC will run more smoothly. One reason your Windows 10 PC may feel sluggish is that you’ve got too many programs running in the background - programs that you rarely or never use. Desktop users have no reason to choose “Power saver,” and even laptop users should consider the “Balanced” option when unplugged - and “High performance” when connected to a power source. “High performance” gives you the most oomph, but uses the most power “Balanced” finds a happy medium between power use and better performance and “Power saver” does everything it can to give you as much battery life as possible. To change your power setting, simply choose the one you want, then exit Control Panel. Change your power settings in Control Panel to give your PC a performance boost.
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Online mmo survival games free5/21/2023 25 Valheim Release Date: 2021 Platform: PC, Xbox Series XS, Xbox One. 13 Mortal Online - 64km2 Mortal Online tends to differ from the norm when it comes to being an MMO, as its actually a first-person fantasy online RPG, very much like Elder Scrolls. The “Massively Multiplayer Online” portion of the acronym refers to the games requiring an internet connection as they are played online and they usually involve thousands, if not tens of thousands for some of the larger games, of players in the same play space (usually called a “server”). Likewise, this is an online multiplayer survival game which means that players can link up and go through some PvE. About This Game Last Oasis is a Nomadic Survival MMO. In addition to the roleplaying elements, these games usually feature large expansive worlds to explore, deep narratives, non-player characters (NPCs), plenty of side activities (like fishing, crafting, player housing or mini-games), and more. Open world games, mmorpg, zombies and more. MMORPG is an acronym for “ Massively Multiplayer Online Role-Playing Game” and is usually the term used to describe online games like World of Warcraft (WoW), Final Fantasy XIV, Guild Wars 2, The Elder Scrolls Online and EVE Online.Ĭommon features of an MMORPG are role-playing elements (RPG) like character progression, creating your own character or deciding what class or skills your character will use, questing or going into dungeons, and grouping together in "parties" or "Guilds". See now the 21 best free steam survival games to play on your pc 2022. The most popular type of MMO is the MMORPG.
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Anonymous instagram story viewer5/21/2023 Only a chosen few can see the content designated for this audience, even if you have thousands of other followers. Create a close friends group: Create a select group of Close Friends to share certain content.You can find this option in Settings under Privacy. Make your Instagram profile private: Only your followers can see your Stories if you set your account private.If you know you’ve got a piece of Story-worthy content, but you’re not keen on putting it out there for the whole world to see, Instagram makes it easy to limit Story visibility to specific audiences, and there are a few ways to do so. If the 48-hour period has expired, you will no longer be able to see the list of viewers for these Stories, even if you saved them as highlights. Your next question may be whether you can see who’s viewed your Instagram Story highlights.
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This useful utility is all you'll ever need if you're looking for an easy way to back up and manage media files and data stored on your iOS device.Įditors' note: This is a review of the trial version of PhoneView for Mac 2.9.5. alloc (newmem,2048,'DarkSoulsRemastered. I did my best to enhance the atmosphere without completely changing the feel. I found DS:R to be visually uninteresting, missing the stylistic bloom and distant DOF effects of the PTDE, and also felt it added a bit of unneeded warmth to the color palette. cover the armor getting and item grabbing stuff but there doesnt seem to be one up on how to use the newest version of cheat engine to bonfire warp. This is a ReShade Preset intended to bring a more stylistic look to Dark Souls Remastered. PhoneView for Mac is feature-rich, lightweight, and well worth the price. DARK SOULS: Prepare To Die Edition > Discusiones generales > Detalles del tema. Most weapons with normal mundane scaling use 6554368. One feature which we think some Mac users may miss is the ability to Quick Look items by pressing the space bar. Open WeaponTypeParam Helper, find the ID of the weapon type you want to edit, put it in Address to Use, click Open and go to the very bottom of the offsets list. You will retain all of your weapons, armor and souls, but not unique items like keys or Embers. Our dedicated proxy is ideal for search engines, promotions in social networks, mass posting on forums, placing ads - like on CraigsList, multiple account, for registrations, sneakers cop (AIOBOT). Upon completing Dark Souls, you are given the option to restart the game in a New Game + Mode. PhoneView is a communications tool allowing you to view, save and print all of your iPhone and iPad messages, WhatsApp messages, voicemail and other data directly on your Mac.įind out how this tool can help you overcome your marketing challenges. Dark souls remastered cheat engine table. Activate the trainer options by checking boxes or setting values from 0 to 1 You do not have the required permissions to view the files attached to this post. Click the PC icon in Cheat Engine in order to select the game process. #Phoneview by ecamm pdf#Ī really nice touch is the ability to save conversations from Messages.app as text or PDF files for desktop viewing and backup. How to use this cheat table Install Cheat Engine Double-click the. Explore and compare features and benefits of PhoneView. In addition to letting you explore and back up media files stored on your iOS device, this app also lets you extract data such as contacts, call logs, notes, bookmarks, and Web browsing history. You do not have the required permissions to view the files attached to this post. Activate the trainer options by checking boxes or setting values from 0 to 1. With PhoneView, you can view, convert, save and print all of your WhatsApp messages, text messages into pdf, iPhone and iPad. Click the PC icon in Cheat Engine in order to select the game process. In terms of transfer speeds, the program averages around 10MB/s. You can drag and drop files between the app and the Finder or the Desktop with ease, but you cannot drag multiple items.
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Mac dvdripper pro windows5/21/2023 Converting a 5-min 4k video that used to take about 16 mins, now needs 1 min only on an Intel/Nvidia/AMD/M1 integrated graphic card, with best balance in quality and size.įor Windows OS users, click to get Windows version Holiday Offer: $29.95, $19. Unique! It achieves record-setting "LEVEL-3" hardware acceleration.Copy DVD to hard drive and USB without quality loss. Update constantly to rip any of the newly released DVDs. Convert DVD to the formats for iPhone, iPod, iPad/iPad 2/iPad 3, PSP, Apple TV, Zune, and mobile phone. Easy video editor: Edit 4K/HD videos like trim, crop, merge, rotate, subtitle and more at your fingertips resize 4K/2.7K/1080p video to be smaller for faster uploading and space saving. 1.The DVD ripper helps to backup and rip DVD to AVI, MP4, FLV, WMV, MOV, MPEG, 3GP formats.Facebook and Vimeo and capture anything on desktop screen with high quality. Download & Record: Download video/music from 1000+ sites, inlc.Convert to any format: Convert all types of media file, including AV1, MP4, HEVC, H264, MOV, MKV, AVI, MTS and make them playable on Mac, mobiles, TV, etc.World's No.1 fast with best quality-size tradeoff. MacX Video Converter Pro One-in-a-generation video transcoding software architected specifically for 4K UHD. Updated! The only tool for all new DVDs, 99-title DVDs, damaged & unplayable DVDs 200% the current industry speed by pioneering Intel QSV/Nivida CUDA/NVENC/Apple M1/M2 (Pro/Max/Ultra).įor Windows OS users, click to get Windows version Holiday Offer: $44.95, $34.95.Backup DVD to ISO Image, MPEG2 and MKV The 4 copy modes let you clone DVD to ISO image at 1:1 image ratio copy main/full title content to MPEG-2 with original video and 5.1 Channel AC3/DTS Audio backup DVD to MKV with selected video/audio/subtitle tracks.3 steps only - throw disc, choose output, and done! Rip DVD to MP4 for iPhone iPad Android on Mac Fast digitize DVD to MP4, MOV, HEVC, H.264, MPEG, MP3, etc in 5 mins, so that you can store them on Mac hard drive/NAS/USB, view on iPhone, iPad, Android, edit in iMovie, upload to YouTube, and enjoy them on big-screen TV.World's No.1 fast speed and intact quality. MacX DVD Ripper Pro - Must-have DVD ripper to digitize any old or new DVDs to hard drive, iPhone, iPad, Apple TV, etc.
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Usb block charger us camera5/21/2023 This option also allows you to select Looped recording. You can then select record all day, scheduled recording times, or motion recording. Looks like an ordinary USB block charger except this one contains a hidden camera with built-in SD card recorder. Q: How do I record onto the SD card?Ī: Go into Device settings on the application and choose SD Card Record Config. Q: Does this work as a charger as well?Ī: Yes the USB port functions as an actual charger. Follow the directions above to connect it to your home WIFI. If you are connected to the device's unique WIFI, it is only going to work when you are in within range. How do I see it when I leave the house?Ī: Make sure you connect the device to your personal WIFI network. Q: I can only see this device when I am within range. Choose the sensitivity for motion and make sure push notifications is selected. Text message notifications of any motion to phoneįAQ Q: How do I configure the device for text message notifications?Ī: Go into device settings on the application and select Alarm config. Time and date stamped video and audio recordings.Records high definition 1080P video as well as audio.If you are going out of town or need a camera to watch your home or office, this is the perfect solution. Asani Hidden Spy Camera USB Charger, Office & Home Security Nanny Cam with SD Card Surge Protection, Motion Detection, Full HD Video, Connects to Smartphone, Secret Camera for Elderly Parents, Pets 3.7 (644) Save 14 239927. The camera is simple to use and installs within minutes. Recordings can be saved onto the phone or onto a micro SD card. Just keep an iPhone or Android cable connected to the device and any unsuspected visitor will have no idea this device is a camera. ) specializes in the wholesale distribution of world class cable assemblies for home theater, PC, and high technology. The camera is virtually undetectable and can even be used as a charger. USB Wall Charger Charger Plug Block Power Charging Adapter for Camera PC. This WIFI plug camera is one of the most advanced cameras that streams in 1080P high definition resolution. 3PCS 3 Port Fast Charger QC 3.0 USB Charging Block Wall Power Adapter US Plug. Most WIFI cameras are difficult to conceal and provide poor picture quality. The camera is now connected to the WIFI network and can be viewed remotely from any location.Select your personal WIFI from the list and put in the correct WIFI password. Click the gear icon on the right and select device settings.Click Search (Lan) and select the device. Click the button that says Add new online camera. The program should add the camera automatically, but if it doesn't Click the + Button on the top right. Go into phone's WIFI settings and connect to camera's unique WIFI (Ex: GO*******).Download free app called "LookCam" in app store or Google Play Store Hidden Camera USB Charger Camera WiFi USB Hub Spy Camera Nanny Cam HD Wireless Security Cameras Indoor USB Tower Covert Cam Motion Detection for Home Office Surveillance. Not included with Pixel 6 and Pixel 6 Pro.The HD wall plug camera installs within minutes and simply involves the installation of a free app on the computer. Contents: Streetwise Fully Functional Block Charger DVR 8GB microSD card USB 2. The camera supports up to a 64 GB micro SD card and recordings can be played back from a smart phone or a computer. Functioning USB 2.0 charger will recharge most USB enabled devices One standard charge USB port One Rapid-Charge USB port Power Source: standard AC outlet Weight: 0.12 lbs. The camera streams and records video in 1080P resolution. It just plugs right into the wall outlet for discreet video recording. It is disguised to look like a wall plug and is simple to install. The HD USB hidden Wall Outlet Video Camera is a high definition video camera that can be accessed using a smart phone such as an Android or iPhone.
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Fundoscopic exam findings5/21/2023 In the majority of patients, WM follows Monoclonal Gammopathy of Undetermined Significance (MGUS). The two main landmarks of this disease are bone marrow infiltration with clonal lymphoplasmacytic cells and IgM proliferation. WM is a lymphoproliferative B-cell disorder that is an indolent form of B-cell non-Hodgkin’s lymphoma, also known as lymphoplasmacytic lymphoma. Waldenstrom macroglobulinemia is characterized by cytopenia due to bone marrow infiltration, anemia, lytic bone disease, organomegalies, diffuse pulmonary infiltrates or pleural effusion due to lymphoplasmacytic infiltration of the parenchyma, and malignant infiltration of the bowel, stomach, skull base, orbit, and CNS. Heredity (certain mutated genes) and certain autoimmune diseases like Sjogren syndrome also increase the risk of developing WM. There are some studies showing an association between Hepatitis C and WM. Additionally, having a pre-existing IgM–Monoclonal Gammopathy of Undetermined Significance (MGUS) significantly increases the risk of developing WM later in life. About 40% of patients with WM will have retinal issues due to serum hyperviscosity. WM is rare in patients younger than 50 years old. About 5% of the patients are Black and 55% to 70% are men. WM is found to be more prevalent amongst Caucasians and males. This accounts for 1-2% of hematological cancers. Waldenstrom macroglobulinemia has an incidence of 3 per million people per year. Serum hyperviscosity leading to vascular disturbances plays a major role in the microvascular changes of the retina causing vascular dilation. Deletions in 6q21-22.1 were found in majority of patients with WM, and B-cell disorders were also found in first degree relatives of these patients. WM is primarily considered a sporadic disease, but some studies have suggested a possibility of a single genetic defect. Marked venous engorgement (sausaging) is seen along with optic nerve edema. įigure 1: Hyperviscosity-related retinopathy due to Waldenstrom macroglobulinemia in the right eye. Ocular manifestations of the disease include infiltration of the conjunctivae, malignant vitritis, and hyperviscosity-related retinopathy (Figure 1). Symptoms include vertigo, headache, ataxia, diplopia, nystagmus, and coma. Perivascular malignant infiltration occurs as a result of long-standing hyperviscosity and secondary CNS vascular hyperpermeability. Patients present with cytopenias due to bone marrow infiltration, lytic bone disease, hepatomegaly, splenomegaly, lymphoplasmacytic infiltration of the pulmonary parenchyma, or Bing-Neel syndrome.īing-Neel syndrome is a rare complication due to lymphoplasmacytoid infiltration and IgM deposits in the CNS. Mast cells also increase significantly in the bone marrow of these patients while overexpressing CD40 Ligand, an inducer of B-cell proliferation. In patients with WM, the bone marrow or the lymph nodes are occupied by pleomorphic B lymphocytes in various maturation stages ranging from small lymphocytes, lymphoplasmacytoid cells with basophilic cytoplasm to plasma cells. Waldenstrom macroglobulinemia (WM) is a malignant lymphoplasmo-proliferative disorder which overproduces IgM, a monoclonal pentameric immunoglobulin. Waldenstrom macroglobulinemia, a type of non-Hodgkin lymphoma, is also known as lymphoplasmacytic lymphoma. |